Ozempic and suchlike...know anybody on 'em?

[gremlin]

My sister, who has always struggled with her weight is quite open about having the jabs to lose weight. As she put it so succinctly, 'Fuck dieting and exercise'.

I reckon two other ladies I know have been having them, as they've gone from 'Rubenesque' to 'Gaunt' in a few months. All well and good, but what happens when they stop taking them? If in fact, they do. Long term health implications? Or a case of Back to Fat?

[KungFooBob]

Have you not been listening to Radio Two this afternoon, it's been the topic of conversation on the Jeremy Vine show (who's on holiday so it's being presented by Tina)?

[gremlin]

Have you not been listening to Radio Two this afternoon, it's been the topic of conversation on the Jeremy Vine show (who's on holiday so it's being presented by Tina)?

Nah. In the office (with one of said ladies...shhh)

I was reading on the BBC about what happens when people do stop taking them. Hardly a surprise...wait for it...they put the weight straight back on if they go back to their old ways. According to sis, they really suppress your appetite, although she did seem to be knocking back copious amounts of red wine when I saw her on Saturday.

The other lady I suspect of fat-jabbing also has various injections into her face at regular intervals and spends a small fortune on ointments and creams to try to hold back the years.

Funny what people do to their bodies in the name of beauty.

[Count Steer]

My sister, who has always struggled with her weight is quite open about having the jabs to lose weight. As she put it so succinctly, 'Fuck dieting and exercise'.

I reckon two other ladies I know have been having them, as they've gone from 'Rubenesque' to 'Gaunt' in a few months. All well and good, but what happens when they stop taking them? If in fact, they do. Long term health implications? Or a case of Back to Fat?

Seems there's a tendency to put it back on.

https://www.bbc.co.uk/news/articles/cwy3jg20j1ro

If you search 'weight loss' on the BBC site there's quite a bit on implications and the perils of self medicating etc. (The missus heard a radio prog and was a bit about the ready availability without any medical oversight).

Edit: looks like you've seen the link.

[Horse]

IIRC there are concerns about other health problems from the jabs.

Weight loss injections, while effective for some, can carry potential health risks. Common side effects include nausea, vomiting, diarrhea, and constipation. More serious, but less frequent, side effects can include gallbladder issues, pancreatitis, and kidney problems. It's crucial to consult with a healthcare professional before starting any weight loss injection to assess individual suitability and potential risks.
Common Side Effects:
Gastrointestinal Issues: Nausea, vomiting, diarrhea, and constipation are frequently reported.
Injection Site Reactions: Some individuals may experience mild allergic reactions at the injection site, such as redness or itching.
Fatigue: Feeling tired or lethargic is another common side effect.
Serious Side Effects:
Pancreatitis: Inflammation of the pancreas, which can cause severe abdominal pain.
Gallbladder Disease: Including gallstones and inflammation of the gallbladder.
Kidney Problems: In rare cases, these injections may affect kidney function.
Hypoglycemia: Low blood sugar, particularly in individuals with diabetes.
Other Rare Side Effects: These may include depression and suicidal ideation.

Fat loss injections like Ozempic can impact oral health due to side effects like increased acid reflux, dry mouth, and nausea, potentially leading to tooth erosion. The combination of these factors can increase the risk of enamel erosion, sensitivity, and decay.

Apart from that, all fine

[Mr Moofo]

IIRC there are concerns about other health problems from the jabs.

Weight loss injections, while effective for some, can carry potential health risks. Common side effects include nausea, vomiting, diarrhea, and constipation. More serious, but less frequent, side effects can include gallbladder issues, pancreatitis, and kidney problems. It's crucial to consult with a healthcare professional before starting any weight loss injection to assess individual suitability and potential risks.
Common Side Effects:
Gastrointestinal Issues: Nausea, vomiting, diarrhea, and constipation are frequently reported.
Injection Site Reactions: Some individuals may experience mild allergic reactions at the injection site, such as redness or itching.
Fatigue: Feeling tired or lethargic is another common side effect.
Serious Side Effects:
Pancreatitis: Inflammation of the pancreas, which can cause severe abdominal pain.
Gallbladder Disease: Including gallstones and inflammation of the gallbladder.
Kidney Problems: In rare cases, these injections may affect kidney function.
Hypoglycemia: Low blood sugar, particularly in individuals with diabetes.
Other Rare Side Effects: These may include depression and suicidal ideation.

Fat loss injections like Ozempic can impact oral health due to side effects like increased acid reflux, dry mouth, and nausea, potentially leading to tooth erosion. The combination of these factors can increase the risk of enamel erosion, sensitivity, and decay.

Apart from that, all fine

But if you are obese you risk strokes, heart attacks, diabetes, asthma related issues and a certain early death. I guess it isall about checks and balances.
I would think that looking at the fat silhouette of most folks in the UK and the exponential growth in diabetes, I think we should make Ozempic complusory for most people whilst banning them from takeaways

[Trinity765]

Yes. Me.

I took Mounjaro in November and December last year and lost a stone and a half. Between January and July I'd put half of that back on and I'm now six weeks back on it and another stone down. I don't need to lose anymore as I can get my leathers on comfortably and will lose a bit while I'm travelling for eight weeks.

The side effects that I've had are a tiredness and extreme weight loss. I have no appetite at all and yet food still tastes great. I'm eating mainly protein, keeping my fluids up and take electrolytes and multi vits. This time I'm also exercising and doing a lot of strengthening exercises. I feel great and ready for the long tour I'm doing.

Most of the side effects that I've seen are to be expected with an extreme calorie deficit and not directly because of the weight loss meds.

I asked a doctor friend what she thought of them and she didn't say anything negative, only that research will narrow down exactly what the drugs are doing which will lead to a "simpler" drug that just produces the weight loss with less side effects.

Someone at work said "You want to try that Mounjaro as everyone is on it". I think they may be right as I know so many people who are taking it - I guess some wouldn't mention as they'd rather you believed it was their own will power. Some extremely overweight people I know have lost up to four stone.

What happens when you stop taking it? You get hungry - simple as.

It's totally open to abuse - it was so easy to get and I could have lied, therefore tighter controls will eventually be brought in.

[ZRX61]

I was on a half dose of Ozempic for diabetes until 3 or 4 weeks ago*. The dosage for weight loss is twice the standard dose for diabetes. I had some mild side effects, but nothing drastic. I can't imagine how fucking dire twice the full dose would be.

* Governor Newsom blew the budget by handing over $9BIllion to give *free* health care to illegals.. & had to increase costs for the rest of us to cover the loss... in my case the Ozempic went from $10/month to $1176.99... I didn't bother picking up the refill.

[Trinity765]

I was on a half dose of Ozempic for diabetes until 3 or 4 weeks ago*. The dosage for weight loss is twice the standard dose for diabetes. I had some mild side effects, but nothing drastic. I can't imagine how fucking dire twice the full dose would be.

* Governor Newsom blew the budget by handing over $9BIllion to give *free* health care to illegals.. & had to increase costs for the rest of us to cover the loss... in my case the Ozempic went from $10/month to $1176.99... I didn't bother picking up the refill.

Cost here (free on NHS for diabetes) is £130 a month. The dose starts low and increases.

[ZRX61]

Cost here (free on NHS for diabetes) is £130 a month. The dose starts low and increases.

Here's it's .25mg for three weeks (one shot a week), then .5mg for three weeks, then full 1mg dose. .5 worked for me so I stayed at that level.
Weight loss is 2mg/week. It works for weight loss because it basically causes gastric paralysis... if ya full of shit all the time you don't want to eat.

[MrLongbeard]

A consultant I saw a year or two back suggested I be put on it, but nothing came of it (likely my area is one of the many that aren't prescribing it), now I get to do the boring ass low carb dance instead, yay.

No great surprise buying it privately can be abused, what is a surprise is that the vast majority put the weight back on again after, you've recognised you're chunky / an unhealthy weight, you shell out hundreds and hundreds of quid over the course of 6 / 12 months and then go back to eating as you used to, at what point in the never ending cycle do you think 'hmmmm, I need to come at this from another direction?"

A little bounce back is understandable, but you've broken the habit of overeating / constant snacking, just stick with not eating as much as you did, replace unhealthy foods with healthy ones whilst you're taking the drug so they become the norm, FFS if I can go from 2 sharing bags of crisps a week to 2 bags of celery and a bag of oranges any bugger can.

Now if you'll excuse me I've got half a bowl of cold rice, and some shitty fish to have for my tea :ralf:

[Sunny]

I know a few people on it. A couple who've lost upwards of three stone. One of whom had 'sulphur burps' as a side effect, which sounds rank. Another who went on it two weeks ago and has already lost 8 pounds.

I've been idly meaning to shift a stone/stone and a half for a while,(read: a few years), but frankly couldn't be arsed. Started contemplating the jabs - though not being officially overweight I didn't know if I'd qualify - then thought maybe I should give the traditional method of watching what I'm shoving in my fat mouth first.

(I've been calorie counting using the MyFitnessPal app, and despite having gone on holiday twice in the last six weeks, I've managed to shift a stone over the last three months, with minimal real effort. Let's see if that final half stone pisses off before the end of the summer )

[demographic]

Woman I meet up with most workday mornings to walk our dogs is on it and she started off at 21 stone and IIRC is about 13 stone now.
She used to have bad joint pains and so on and sure seems happier about it.

Its quite possible she gains weight afterwards but as far as I can tell she's pretty pragmatic about it. At least she's got a good start on losing weight.

[Le_Fromage_Grande]

Wouldn't it be easier, more fun and possibly cheaper to take speed, it's an appetite suppresant.

[Sunny]

I also have mates - one in particular, who's now had a gastric sleeve to be done with it, and promptly lost 11.5 stone - who can lose many stones through willpower, then put em back on. So it's only the same kind of thing really.

[Sunny]

Wouldn't it be easier, more fun and possibly cheaper to take speed, it's an appetite suppresant.

Mmm. Tasty amphetamines. Another thing I had to learn willpower over, back in the day

[Taipan]

The downsides that I can see are more and more Docs are talking about the links to Pancreatitis and of course the awful "Ozempic smile' is another unwanted side effect. Couple of people at work look like AIDS victims did in the 80s. I guess you have to learn when to stop?

https://www.medicalnewstoday.com/articl ... de-effects

Upsides, well weight loss obvs. But there's gotta better and safer ways to achive your weight loss goal?

[Mr Moofo]

I was on a half dose of Ozempic for diabetes until 3 or 4 weeks ago*. The dosage for weight loss is twice the standard dose for diabetes. I had some mild side effects, but nothing drastic. I can't imagine how fucking dire twice the full dose would be.

* Governor Newsom blew the budget by handing over $9BIllion to give *free* health care to illegals.. & had to increase costs for the rest of us to cover the loss... in my case the Ozempic went from $10/month to $1176.99... I didn't bother picking up the refill.

Cost here (free on NHS for diabetes) is £130 a month. The dose starts low and increases.

You are in a similar area to me. I asked to be put on it for controlling diabetes. I was told i wasn’t fat enough and need a BMI of over 35!

[Mr. Dazzle]

You are in a similar area to me. I asked to be put on it for controlling diabetes. I was told i wasn’t fat enough and need a BMI of over 35!

Sounds like a challenge if ever I heard one.

[Count Steer]

People want easy, fast results that require no effort. It's human nature I suppose and the pharmaceutical industry are only too happy to oblige when there's such a large market willing to pay the ££. The NHS will be pleased if it cuts the obesity-related bills too.

Hardly any downsides really apart from possible side effects (and the risks of self-medication with no medical oversight) - unless there are some long term use issues that haven't shown up yet. The drugs should get cheaper too.

Personally I try to take as few or as poss (and have avoided getting put on anything that you have to take long term until last month* ) I still have my vaccination jabs and will, reluctantly, pop pills if I really need to and would, in certain circumstances ie if I ever needed to shift weight fast eg for an op, use a fat jab but otherwise I'll stick to the long-haul/change lifestyle approach. (Which, I must say, is much easier to do in retirement than when I was working ).

* If I ever found a way to reduce my high blood pressure - which has been high for umpteen years - I'd stop taking them too. I've tried everything. From weight loss to yoga, the lot I guess it's hereditary, inherent or something. The pills work but I don't feel any different...maybe slightly less healthy if anything.